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Tirzepatide

Rx only

Part of Weight Loss & Metabolic The most-searched category on the platform

Clinical dosing reference — FDA-approved only

Shown only for prescription drugs with an FDA label. This describes how these medications are typically prescribed, not a recommendation for you specifically — your prescriber sets and adjusts your actual dose.

Tirzepatide (Zepbound)

Titration
Weekly subcutaneous injection, starting at 2.5 mg (a treatment-initiation dose, not a maintenance dose). After 4 weeks, increased to 5 mg, then optionally in 2.5 mg increments every 4+ weeks up to a maximum of 15 mg.
Maintenance dose
5 mg, 10 mg, or 15 mg once weekly — many patients stay at 5 mg or 10 mg rather than titrating to the maximum.
Trial results
In the SURMOUNT-1 trial (72 weeks), participants on the 15 mg dose lost a mean of 20.9% of body weight, vs. 3.1% on placebo.
Source: FDA prescribing information (DailyMed)

Other compounds in this category have no FDA-approved human dosing to cite — see the note below.

Recent research

Live results from PubMed, the NIH’s public database of biomedical literature.

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Tirzepatide is an FDA-approved prescription therapeutic available only through a licensed provider. This page does not recommend or endorse use outside of professional medical guidance. See the full disclaimer.
Tirzepatide — Peptide Guide | A Peptide Store